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Thank you for developing this useful tool. I find it particularly valuable for visualizing alignments of highly repetitive sequences and their mutational patterns, such as those in centromeres. Given the challenges posed by the highly repetitive nature of such sequences, traditional alignment tools like minimap2, mummer, or the recently developed Unialigner may not perform optimally. However, the word-based alignment strategy employed by redotable appears to address this issue effectively.
While the current version of redotable lacks the ability to display specific coordinate positions of a diagonal line, I'm wondering if it's feasible to include a feature that allows the software to output alignment coordinates.
Best regards,
Xiao
The text was updated successfully, but these errors were encountered:
Dear Simon,
Thank you for developing this useful tool. I find it particularly valuable for visualizing alignments of highly repetitive sequences and their mutational patterns, such as those in centromeres. Given the challenges posed by the highly repetitive nature of such sequences, traditional alignment tools like minimap2, mummer, or the recently developed Unialigner may not perform optimally. However, the word-based alignment strategy employed by redotable appears to address this issue effectively.
While the current version of redotable lacks the ability to display specific coordinate positions of a diagonal line, I'm wondering if it's feasible to include a feature that allows the software to output alignment coordinates.
Best regards,
Xiao
The text was updated successfully, but these errors were encountered: