diff --git a/src/build/generate-contributions.ts b/src/build/generate-contributions.ts
index 67b040fcc..0c10ce78d 100644
--- a/src/build/generate-contributions.ts
+++ b/src/build/generate-contributions.ts
@@ -357,6 +357,14 @@ const nodeBaseConfigurationAttributes: ConfigurationAttributes<INodeBaseConfigur
     description: refString('node.versionHint.description'),
     default: 12,
   },
+  pathMapping: {
+    type: 'object',
+    items: {
+      type: 'string',
+    },
+    markdownDescription: refString('node.pathMapping.description'),
+    default: {},
+  },
 };
 
 /**
diff --git a/src/build/strings.ts b/src/build/strings.ts
index c75ad8a6b..8be0d67fb 100644
--- a/src/build/strings.ts
+++ b/src/build/strings.ts
@@ -225,6 +225,8 @@ const strings = {
   'node.sourceMapPathOverrides.description':
     'A set of mappings for rewriting the locations of source files from what the sourcemap says, to their locations on disk.',
   'node.sourceMaps.description': 'Use JavaScript source maps (if they exist).',
+  'node.pathMapping.description':
+    'A mapping of folders from one path to another. To resolve scripts to their original locations. Typical use is to map scripts in `node_modules` to their sources that locate in another folder.',
   'node.stopOnEntry.description': 'Automatically stop program after launch.',
   'node.timeout.description':
     'Retry for this number of milliseconds to connect to Node.js. Default is 10000 ms.',
diff --git a/src/configuration.ts b/src/configuration.ts
index 5dd5ddd36..02c81846c 100644
--- a/src/configuration.ts
+++ b/src/configuration.ts
@@ -322,6 +322,13 @@ export interface INodeBaseConfiguration extends IBaseConfiguration, IConfigurati
    * with `--inpect-brk`.
    */
   continueOnAttach?: boolean;
+
+  /**
+   * A mapping of folders from one path to another. To resolve scripts to their
+   * original locations. Typical use is to map scripts in `node_modules` to their
+   * sources that locate in another folder.
+   */
+  pathMapping: PathMapping;
 }
 
 export interface IConfigurationWithEnv {
@@ -420,7 +427,7 @@ export interface INodeLaunchConfiguration extends INodeBaseConfiguration, IConfi
   attachSimplePort: null | number;
 
   /**
-   * Configures how debug process are killed when stopping the sesssion. Can be:
+   * Configures how debug process are killed when stopping the session. Can be:
    *  - forceful (default): forcefully tears down the process tree. Sends
    *    SIGKILL on posix, or `taskkill.exe /F` on Windows.
    *  - polite: gracefully tears down the process tree. It's possible that
@@ -833,6 +840,7 @@ const nodeBaseDefaults: INodeBaseConfiguration = {
   resolveSourceMapLocations: ['**', '!**/node_modules/**'],
   autoAttachChildProcesses: true,
   runtimeSourcemapPausePatterns: [],
+  pathMapping: {},
 };
 
 export const terminalBaseDefaults: ITerminalLaunchConfiguration = {
@@ -884,6 +892,7 @@ export const nodeLaunchConfigDefaults: INodeLaunchConfiguration = {
   profileStartup: false,
   attachSimplePort: null,
   killBehavior: KillBehavior.Forceful,
+  pathMapping: {},
 };
 
 export const chromeAttachConfigDefaults: IChromeAttachConfiguration = {
diff --git a/src/targets/node/nodeSourcePathResolver.ts b/src/targets/node/nodeSourcePathResolver.ts
index 9b7978835..144a0de57 100644
--- a/src/targets/node/nodeSourcePathResolver.ts
+++ b/src/targets/node/nodeSourcePathResolver.ts
@@ -9,23 +9,27 @@ import { ILogger } from '../../common/logging';
 import { fixDriveLetterAndSlashes, properResolve } from '../../common/pathUtils';
 import { SourceMap } from '../../common/sourceMaps/sourceMap';
 import {
+  defaultPathMappingResolver,
   getComputedSourceRoot,
   getFullSourceEntry,
   moduleAwarePathMappingResolver,
 } from '../../common/sourceMaps/sourceMapResolutionUtils';
 import { IUrlResolution } from '../../common/sourcePathResolver';
 import * as urlUtils from '../../common/urlUtils';
-import { AnyLaunchConfiguration, AnyNodeConfiguration } from '../../configuration';
+import { AnyLaunchConfiguration, AnyNodeConfiguration, PathMapping } from '../../configuration';
 import { ILinkedBreakpointLocation } from '../../ui/linkedBreakpointLocation';
 import { ISourcePathResolverOptions, SourcePathResolverBase } from '../sourcePathResolver';
 
 interface IOptions extends ISourcePathResolverOptions {
   basePath?: string;
+  pathMapping: PathMapping;
 }
 
 const localNodeInternalsPrefix = 'node:';
 
 export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
+  private hasPathMapping: boolean;
+
   public static shouldWarnAboutSymlinks(config: AnyLaunchConfiguration) {
     return 'runtimeArgs' in config && !config.runtimeArgs?.includes('--preserve-symlinks');
   }
@@ -37,6 +41,7 @@ export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
       sourceMapOverrides: c.sourceMapPathOverrides,
       remoteRoot: c.remoteRoot,
       localRoot: c.localRoot,
+      pathMapping: c.pathMapping,
     };
   }
 
@@ -47,6 +52,7 @@ export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
     protected readonly logger: ILogger,
   ) {
     super(options, logger);
+    this.hasPathMapping = Object.keys(this.options.pathMapping).length > 0;
   }
 
   /**
@@ -65,6 +71,30 @@ export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
     return this.options;
   }
 
+  /**
+   * map remote path to local path and apply the pathMapping option
+   *
+   * @param scriptPath remote path
+   * @returns mapped path
+   */
+  private async rebaseRemoteWithPathMapping(scriptPath: string): Promise<string> {
+    const mapped = this.rebaseRemoteToLocal(scriptPath);
+
+    if (this.hasPathMapping) {
+      const mapped2 = await defaultPathMappingResolver(
+        mapped,
+        this.options.pathMapping,
+        this.logger,
+      );
+
+      if (mapped2 && (await this.fsUtils.exists(mapped2))) {
+        return mapped2;
+      }
+    }
+
+    return mapped;
+  }
+
   /**
    * @override
    */
@@ -89,7 +119,7 @@ export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
 
     const absolutePath = urlUtils.fileUrlToAbsolutePath(url);
     if (absolutePath) {
-      return this.rebaseRemoteToLocal(absolutePath);
+      return await this.rebaseRemoteWithPathMapping(absolutePath);
     }
 
     // It's possible the source might be an HTTP if using the `sourceURL`
@@ -111,7 +141,7 @@ export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
     }
 
     const withBase = properResolve(this.options.basePath ?? '', url);
-    return this.rebaseRemoteToLocal(withBase);
+    return await this.rebaseRemoteWithPathMapping(withBase);
   }
 
   /**
@@ -175,6 +205,6 @@ export class NodeSourcePathResolver extends SourcePathResolverBase<IOptions> {
       );
     }
 
-    return this.rebaseRemoteToLocal(url) || url;
+    return await this.rebaseRemoteWithPathMapping(url);
   }
 }
diff --git a/src/test/node/node-source-path-resolver.test.ts b/src/test/node/node-source-path-resolver.test.ts
index 79782f243..7f9007ef7 100644
--- a/src/test/node/node-source-path-resolver.test.ts
+++ b/src/test/node/node-source-path-resolver.test.ts
@@ -20,6 +20,7 @@ describe('node source path resolver', () => {
       remoteRoot: null,
       localRoot: null,
       sourceMapOverrides: { 'webpack:///*': `${__dirname}/*` },
+      pathMapping: {},
     };
 
     it('resolves absolute', async () => {
@@ -95,6 +96,35 @@ describe('node source path resolver', () => {
       );
     });
 
+    it('applies pathMapping option', async () => {
+      const r = new NodeSourcePathResolver(
+        {
+          realPath: fsUtils.realPath,
+          readFile: fsUtils.readFile,
+          exists: async p => p === '/lib/index.js',
+        },
+        undefined,
+        {
+          ...defaultOptions,
+          pathMapping: {
+            '/src': '/lib',
+          },
+        },
+        Logger.null,
+      );
+
+      expect(await r.urlToAbsolutePath({ url: 'file:///src/index.js' })).to.equal('/lib/index.js');
+      expect(await r.urlToAbsolutePath({ url: 'file:///src/not-exist.js' })).to.equal(
+        '/src/not-exist.js',
+      );
+      expect(await r.urlToAbsolutePath({ url: 'file:///src2/index.js' })).to.equal(
+        '/src2/index.js',
+      );
+      expect(await r.urlToAbsolutePath({ url: 'file:///test/src/index.js' })).to.equal(
+        '/test/src/index.js',
+      );
+    });
+
     describe('source map filtering', () => {
       const testTable = {
         'matches paths': {