diff --git a/.changeset/nervous-jeans-obey.md b/.changeset/nervous-jeans-obey.md
new file mode 100644
index 000000000000..4256c59b49b4
--- /dev/null
+++ b/.changeset/nervous-jeans-obey.md
@@ -0,0 +1,5 @@
+---
+"wrangler": patch
+---
+
+Fix to not require local connection string when using Hyperdrive and wrangler dev --remote
diff --git a/.github/workflows/e2e.yml b/.github/workflows/e2e.yml
index 1da2472650f6..c33932498ba2 100644
--- a/.github/workflows/e2e.yml
+++ b/.github/workflows/e2e.yml
@@ -48,6 +48,7 @@ jobs:
         env:
           CLOUDFLARE_API_TOKEN: ${{ secrets.TEST_CLOUDFLARE_API_TOKEN }}
           CLOUDFLARE_ACCOUNT_ID: ${{ secrets.TEST_CLOUDFLARE_ACCOUNT_ID }}
+          HYPERDRIVE_DATABASE_URL: ${{ secrets.TEST_HYPERDRIVE_DATABASE_URL}}
           WRANGLER: node --no-warnings ${{ github.workspace}}/packages/wrangler/bin/wrangler.js
           WRANGLER_IMPORT: ${{ github.workspace}}/packages/wrangler/wrangler-dist/cli.js
           NODE_OPTIONS: "--max_old_space_size=8192"
diff --git a/packages/wrangler/e2e/dev-with-resources.test.ts b/packages/wrangler/e2e/dev-with-resources.test.ts
index f464c54b9ab2..fc1a2ee04a20 100644
--- a/packages/wrangler/e2e/dev-with-resources.test.ts
+++ b/packages/wrangler/e2e/dev-with-resources.test.ts
@@ -580,6 +580,35 @@ describe.sequential.each(RUNTIMES)("Bindings: $flags", ({ runtime, flags }) => {
 		);
 	});
 
+	it("exposes Hyperdrive bindings", async () => {
+		const { id } = await helper.hyperdrive(false);
+
+		await helper.seed({
+			"wrangler.toml": dedent`
+					name = "${workerName}"
+					main = "src/index.ts"
+					compatibility_date = "2023-10-25"
+
+					[[hyperdrive]]
+					binding = "HYPERDRIVE"
+					id = "${id}"
+			`,
+			"src/index.ts": dedent`
+					export default {
+						async fetch(request, env) {
+							if (request.url.includes("connect")) {
+								const conn = env.HYPERDRIVE.connect();
+							}
+							return new Response(env.HYPERDRIVE?.connectionString ?? "no")
+						}
+					}`,
+		});
+
+		const worker = helper.runLongLived(`wrangler dev ${flags}`);
+		const { url } = await worker.waitForReady();
+		await fetch(`${url}/connect`);
+	});
+
 	it.skipIf(!isLocal).fails("exposes Pipelines bindings", async () => {
 		await helper.seed({
 			"wrangler.toml": dedent`
@@ -692,7 +721,6 @@ describe.sequential.each(RUNTIMES)("Bindings: $flags", ({ runtime, flags }) => {
 	});
 
 	// TODO(soon): implement E2E tests for other bindings
-	it.todo("exposes hyperdrive bindings");
 	it.skipIf(isLocal).todo("exposes send email bindings");
 	it.skipIf(isLocal).todo("exposes browser bindings");
 	it.skipIf(isLocal).todo("exposes Workers AI bindings");
diff --git a/packages/wrangler/e2e/dev.test.ts b/packages/wrangler/e2e/dev.test.ts
index 423ae226a8af..fbdd45e5b28d 100644
--- a/packages/wrangler/e2e/dev.test.ts
+++ b/packages/wrangler/e2e/dev.test.ts
@@ -653,6 +653,44 @@ describe("hyperdrive dev tests", () => {
 		await socketMsgPromise;
 	});
 
+	it("does not require local connection string when running `wrangler dev --remote`", async () => {
+		const helper = new WranglerE2ETestHelper();
+		const { id } = await helper.hyperdrive(false);
+
+		await helper.seed({
+			"wrangler.toml": dedent`
+					name = "${workerName}"
+					main = "src/index.ts"
+					compatibility_date = "2023-10-25"
+
+					[[hyperdrive]]
+					binding = "HYPERDRIVE"
+					id = "${id}"
+			`,
+			"src/index.ts": dedent`
+					export default {
+						async fetch(request, env) {
+							if (request.url.includes("connect")) {
+								const conn = env.HYPERDRIVE.connect();
+							}
+							return new Response(env.HYPERDRIVE?.connectionString ?? "no")
+						}
+					}`,
+			"package.json": dedent`
+					{
+						"name": "worker",
+						"version": "0.0.0",
+						"private": true
+					}
+					`,
+		});
+
+		const worker = helper.runLongLived("wrangler dev --remote");
+
+		const { url } = await worker.waitForReady();
+		await fetch(`${url}/connect`);
+	});
+
 	afterEach(() => {
 		if (server.listening) {
 			server.close();
diff --git a/packages/wrangler/e2e/helpers/e2e-wrangler-test.ts b/packages/wrangler/e2e/helpers/e2e-wrangler-test.ts
index 293ff896b796..a12a8ea4f061 100644
--- a/packages/wrangler/e2e/helpers/e2e-wrangler-test.ts
+++ b/packages/wrangler/e2e/helpers/e2e-wrangler-test.ts
@@ -124,4 +124,27 @@ export class WranglerE2ETestHelper {
 
 		return name;
 	}
+
+	async hyperdrive(isLocal: boolean): Promise<{ id: string; name: string }> {
+		const name = generateResourceName("hyperdrive");
+
+		if (isLocal) {
+			return { id: crypto.randomUUID(), name };
+		}
+
+		const result = await this.run(
+			`wrangler hyperdrive create ${name} --connection-string="${process.env.HYPERDRIVE_DATABASE_URL}"`
+		);
+		const tomlMatch = /id = "([0-9a-f]{32})"/.exec(result.stdout);
+		const jsonMatch = /"id": "([0-9a-f]{32})"/.exec(result.stdout);
+		const match = jsonMatch ?? tomlMatch;
+		assert(match !== null, `Cannot find ID in ${JSON.stringify(result)}`);
+		const id = match[1];
+
+		onTestFinished(async () => {
+			await this.run(`wrangler hyperdrive delete ${name}`);
+		});
+
+		return { id, name };
+	}
 }
diff --git a/packages/wrangler/src/dev.ts b/packages/wrangler/src/dev.ts
index 3d4a50aaa11f..0fae28516140 100644
--- a/packages/wrangler/src/dev.ts
+++ b/packages/wrangler/src/dev.ts
@@ -1020,7 +1020,12 @@ export function getBindings(
 			process.env[
 				`WRANGLER_HYPERDRIVE_LOCAL_CONNECTION_STRING_${hyperdrive.binding}`
 			];
-		if (!connectionStringFromEnv && !hyperdrive.localConnectionString) {
+		// only require a local connection string in the wrangler file or the env if not using dev --remote
+		if (
+			local &&
+			!connectionStringFromEnv &&
+			!hyperdrive.localConnectionString
+		) {
 			throw new UserError(
 				`When developing locally, you should use a local Postgres connection string to emulate Hyperdrive functionality. Please setup Postgres locally and set the value of the 'WRANGLER_HYPERDRIVE_LOCAL_CONNECTION_STRING_${hyperdrive.binding}' variable or "${hyperdrive.binding}"'s "localConnectionString" to the Postgres connection string.`
 			);
diff --git a/packages/wrangler/turbo.json b/packages/wrangler/turbo.json
index 4647f496f2e3..b4c4fc471697 100644
--- a/packages/wrangler/turbo.json
+++ b/packages/wrangler/turbo.json
@@ -59,7 +59,8 @@
 				"WRANGLER_DISABLE_EXPERIMENTAL_WARNING",
 				"WRANGLER_DISABLE_REQUEST_BODY_DRAINING",
 				"WRANGLER_WORKER_REGISTRY_PORT",
-				"WRANGLER_API_ENVIRONMENT"
+				"WRANGLER_API_ENVIRONMENT",
+				"HYPERDRIVE_DATABASE_URL"
 			]
 		},
 		"test:ci": {