diff --git a/cdap-gateway/src/main/java/io/cdap/cdap/gateway/router/handlers/HttpRequestRouter.java b/cdap-gateway/src/main/java/io/cdap/cdap/gateway/router/handlers/HttpRequestRouter.java
index 3fc932fc2f74..5c0ca922d71e 100644
--- a/cdap-gateway/src/main/java/io/cdap/cdap/gateway/router/handlers/HttpRequestRouter.java
+++ b/cdap-gateway/src/main/java/io/cdap/cdap/gateway/router/handlers/HttpRequestRouter.java
@@ -192,6 +192,30 @@ public void channelInactive(ChannelHandlerContext ctx) {
     ctx.fireChannelInactive();
   }
 
+  /**
+   * [CDAP-21071] Handles the case by stopping the outbound channel of Service -> Router
+   * when the response from Service -> Router is faster than the response from Router to the Client.
+   */
+  @Override
+  public void channelWritabilityChanged(ChannelHandlerContext ctx) throws Exception {
+    if (inflightRequests > 0 && currentMessageSender.outboundChannel != null) {
+      final Channel outboundChannel = ctx.channel();
+      ctx.executor().execute(() -> {
+        // If outboundChannel is not saturated anymore, continue accepting
+        // the incoming traffic from the outbound channel for service<>router.
+        if (outboundChannel.isWritable()) {
+          LOG.trace("Setting message sender's outboundChannel readable.");
+          currentMessageSender.outboundChannel.config().setAutoRead(true);
+        } else {
+          // If outboundChannel is saturated, do not read inboundChannel
+          LOG.trace("Setting message sender's outboundChannel non-readable.");
+          currentMessageSender.outboundChannel.config().setAutoRead(false);
+        }
+      });
+    }
+    ctx.fireChannelWritabilityChanged();
+  }
+
   private ChannelFutureListener getFailureResponseListener(final Channel inboundChannel) {
     if (failureResponseListener == null) {
       failureResponseListener = new ChannelFutureListener() {